1 16
Verified customer

"I covered my mouth at my own kids' weddings. Yellow. Damaged. Bleeding gums. One patch a night. Four months later the surface looked rebuilt — and I stopped hiding."

Elena P. ★★★★★ · 35 · Verified · Verified Buyer
5-in-1 Tideglusib Microneedle Delivery

Prime® Tooth & Gum Care Fast-Dissolving Microneedle Patch

Rebuild enamel & dentin. Kill the tartar line. Stop the jolt. This is not toothpaste.

Rebuild Enamel & Dentin Strengthen Gums Eradicate Tartar & Odor Whitening Stop Sensitivity
4.7 10,715 reviews from people who stopped hiding their smile
60-Day Guarantee — Love your smile or you pay $0.

Yellow tartar you can't brush off. Blood in the sink. That jolt when cold hits exposed dentin. Toothpaste is gone in 90 seconds. Strips never reach the gum line. This patch drives Tideglusib + hydroxyapatite through dissolving microneedles — parked on the tooth and gum line while you sleep — to rebuild enamel & dentin, strengthen gums, break down tartar and odor, whiten, and shut down sensitivity. 5 jobs. One patch. Minutes. Done.

  • Rebuild enamel & dentin. Tideglusib + Wnt signaling — repair from inside, not a surface coat.
  • Eradicate tartar & odor at the gum line. The exact spot a brush never holds.
  • Stop the ice-water jolt. Hydroxyapatite fills micro-gaps. Sensitivity drops. Whitening builds.
  • Dissolves in minutes. Zero drilling. No trays. No peroxide burn. Between dental visits.
Today
Ordered
1–2 days
Order Ready
7–10 days
Delivered

They Stopped Hiding Their Smile.

Enamel. Dentin. Gums. Tartar. Sensitivity. Nightly patch — not a $5,000 chair.

Vincent M. "The tartar line finally broke"

"Years of coffee and smoking left a brown tartar line along my gums no brush, no strip, no paste ever touched. One patch every night. Around week three the buildup lifted and the enamel looked cleaner than it had in a decade. I smile with teeth in photos now."

Vincent M.· Tartar & stains · Age 33· ★★★★★ Verified Buyer
Theodore Y. "The sink doesn't turn pink anymore"

"At 67 my gums were red, swollen, and the sink turned pink every morning. I thought that was just age. A patch after brushing. That's it. Two weeks later the bleeding stopped, the gums looked tighter, and my hygienist asked what I changed before I said a word."

Theodore Y.· Gums · Age 67· ★★★★★ Verified Buyer
Elena P. "I drink iced coffee without the jolt"

"Cold air, ice water, iced coffee — lightning through the tooth every time. That's exposed dentin. One patch a night for a month. The sensitivity shut off. The surface looks brighter and smoother, like the enamel actually filled back in. I don't flinch anymore."

Elena P.· Dentin & sensitivity · Age 35· ★★★★★ Verified Buyer

Still on the Fence?

Does this actually rebuild enamel and dentin?
That's the job. Tideglusib (GSK-3 inhibitor) is designed to switch Wnt signaling back on so dental pulp stem cells can lay down reparative dentin from the inside. Hydroxyapatite fills micro-damage on the enamel surface. This is not a 90-second toothpaste coat. It's nightly, targeted repair at the tooth and gum line. Individual results vary. Not a replacement for a dentist.
Microneedles in my mouth — does it hurt?
No. They're microscopic and dissolve the second they meet saliva. You feel a patch, not a prick. That's how Tideglusib, hydroxyapatite, EGF, CoQ10, resveratrol and triphala get past the surface a brush never holds. No burning gel. No numbing. No drilling.
Why not strips, trays, or a "whitening" toothpaste?
Paste gets spat out in 90 seconds. Strips slide off the front teeth and never sit on tartar at the gum line. Trays are 30 minutes of peroxide. This stays put and does 5 jobs: rebuild enamel & dentin, strengthen gums, eradicate tartar & odor, whiten, stop sensitivity. Once a night. Minutes. Done.
Safe every day — crowns, braces, veneers? When do I see it?
Gentle daily use — no peroxide burn, no harsh abrasives. Comfort and fresher breath show up first. The visible rebuild — brighter enamel, calmer gums, less tartar line — builds over weeks of nightly use. Skip days and you stall it. Works alongside your dentist, not instead of one. Active pain, abscess, loose tooth, dental work in progress, pregnant or nursing: ask your dentist first.
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Made InUSA
Painless& Gentle
DermatologistTested
ClinicallyTested
100%Natural
CrueltyFree
ParabenFree
FragranceFree
5-in-1 Tideglusib Microneedle Delivery

Your Brush Never Reaches
Where Enamel & Dentin Break Down

The tartar line along your gums. Blood in the sink. The jolt when cold hits exposed dentin. Two minutes of scrubbing was never going to rebuild that — because a brush only lasts 90 seconds on the surface.

Applying the Prime Tooth & Gum microneedle patch
How dental problems chain from surface to core
It never stays one small problem

Tartar Today. Bleeding Gums. Exposed Dentin Tomorrow.

Plaque hardens into tartar. Tartar inflames the gum line. Gums pull back. Dentin is exposed — and ice water becomes a gamble. Prime® parks Tideglusib + hydroxyapatite on that exact chain and holds them there while the patch melts — to rebuild enamel & dentin, kill the tartar line, and shut down the jolt.

Tartar LineBleeding GumsExposed DentinIce-Water JoltDull EnamelOdor
START THE NIGHTLY REBUILD →
Targeted Microneedle Delivery

Paste Gets Spat Out.
Tideglusib Stays and Rebuilds.

Toothpaste has 90 seconds. Strips slide off the front teeth. This patch locks onto the gum line and drives actives into enamel and dentin as it dissolves.

1. It Parks on the Gum Line

Press it onto the tooth and gum area you want to rebuild. No trays. No slipping. No swallowing it in 30 seconds.

2. Microneedles Dissolve

Saliva melts the micro-structure in minutes — releasing Tideglusib, hydroxyapatite, CoQ10 and triphala where a brush never holds.

3. Wnt Signaling Does the Work

Minutes of direct contact so Tideglusib can switch repair signaling back on — enamel, dentin, gums. Not a surface coat.

Targeted microneedle dental patch technology
How the actives reach the tooth and gum line
The 5-in-1 Rebuild

Five Jobs.
One Patch a Night.

Prime Tooth & Gum Care patch — pack and application
01

Rebuild Enamel & Dentin

Tideglusib + Wnt signaling — repair from inside, not a 90-second coat.

02

Strengthen Gums

CoQ10 + EGF at the gum line where redness, soreness and bleeding start.

03

Eradicate Tartar & Odor

Breaks the brown line a brush never lifts. Fresh breath, not mint cover.

04

Whitening

Lifts coffee, tea, wine and smoke stains — then rebuilds the surface.

05

Stop Sensitivity

Hydroxyapatite fills micro-gaps so ice water stops being a gamble.

Enamel protection and whitening
Stain lift → dentin rebuild

Whitening That Rebuilds — Not Bleach That Burns

Peroxide strips strip the surface and leave teeth screaming at cold. This works in order: kill the stain, then rebuild enamel with hydroxyapatite and switch dentin repair on with Tideglusib so the tooth ends up brighter, smoother, and actually protected — not raw.

GET THE REBUILD →
Active Ingredients

The Formula That
Turns Repair Back On.

Tideglusib at the core. Hydroxyapatite, CoQ10, EGF, resveratrol, triphala around it. Six actives. One nightly rebuild. Tap to open.

Tideglusib Core Rebuild
GSK-3 inhibitor designed to switch Wnt signaling back on so dental pulp stem cells can lay down reparative dentin from the inside. This is the difference between coating a tooth and rebuilding it. Individual results vary. Draft — legal/medical audit required before live ads.
Hydroxyapatite Enamel
The same mineral enamel is built from. Fills micro-defects on the tooth surface, leaving it smoother, brighter, and better protected — which is why the ice-water jolt eases off.
Coenzyme Q10 Gum Support
The gum-care staple. Supports tissue at the gum line so redness, soreness, and that pink sink start backing off.
Epidermal Growth Factor (EGF) Tissue Care
Supports renewal of irritated gum tissue around the exact zone the patch sits. Firmer, calmer gums — better support for the tooth.
Resveratrol Antioxidant
Antioxidant shield for gum and tooth tissue — helping the mouth stay calmer instead of constantly inflamed.
Triphala Breath & Tartar
Botanical complex for the oral microbiome. Helps break the odor cycle and support a cleaner gum line — fresh, not mint-masked.
Active ingredients formula
★★★★★

"Tideglusib plus hydroxyapatite. That's rebuild, not bleach. I stopped hiding my teeth in photos."

— Verified Buyer · ✓ Confirmed purchase
Dead Simple

Brush. Patch. Sleep. Rebuild Overnight.

1

Brush & Rinse

Clean surface first so Tideglusib lands where enamel and dentin actually need it.

2

Peel & Place

Open a sachet. Press the patch onto the tooth and gum line you're targeting.

3

Let It Dissolve

It melts in minutes. Once a night. Skip days and you stall the rebuild.

Directions for use

✅ GOOD TO KNOW

One patch a night. 7 patches per box. Store cool and dry, away from direct sunlight.

Use on healthy, intact gum tissue. Active tooth pain, abscess, loose tooth, dental work in progress, pregnant or nursing: talk to your dentist first. Stop if irritation appears. Keep out of reach of children. Not a substitute for professional dental care.

Real People · Real Rebuild

The Tartar Line Was Winning.
Then It Wasn't.

Brand-supplied customer photos. Individual results vary with starting condition and nightly consistency.

Before and after — tartar buildup

Tartar line · 47 days

"The brown line along my gums broke. I smile with teeth now."

Before and after — plaque buildup

Heavy plaque · 27 days

"Four weeks of one patch a night. Enamel looks clean again."

Before and after — stains and tartar

Stains & tartar · 24 days

"Coffee and smoking wrecked it. This lifted what brushing never did."

GET THE SAME REBUILD →
In Their Own Words

Don't Take Our Word.
Take Theirs.

Customer review
★★★★★

"The tartar line finally let go"

✓ Verified Buyer
Customer review
★★★★★

"Ice water doesn't jolt anymore"

✓ Verified Buyer
Customers sharing their results
Verified customer reviews
Why People Switch

One Nightly Rebuild
vs. a $5,000 Chair

Prime patch compared to conventional options

Cleanings Wear Off.
Strips Burn. Paste Never Rebuilds.

You've been paying for surface fixes on a dentin problem. This is the part you control — Tideglusib on the gum line, every night, in the minutes you're already at the sink.

✗The dental-debt trap — drill, fill, repeat
✗Peroxide strips that leave dentin screaming at cold
✗Paste spat out in 90 seconds — never reaches Wnt
✓One patch. Rebuild enamel & dentin. Kill tartar. Stop the jolt.
SWITCH TONIGHT →
What's Not In It

Clean Enough
to Rebuild Every Single Night

Zero added — clean formula
Product specifications
99%reported visible tooth-surface improvement
96%noticed better enamel condition
98%reported healthier-feeling gums
97%felt their teeth were stronger

Based on customer feedback surveys. Results vary. Brand must substantiate sample size before live ads.

Try the Rebuild for 60 Nights.
Or You Pay $0.

60-Day Money-Back

Love your smile or a full refund. No forms, no hassle.

Fast Shipping

Ships quickly with tracking on every order.

Gentle Nightly Formula

No peroxide burn. No harsh abrasives. Built for every night.

Real Human Support

Questions? Real people. Fast replies.

Made in the USA GMP-Certified Facility Non-GMO Dye Free Gluten Free 60-Day Guarantee Made in the USA GMP-Certified Facility Non-GMO Dye Free Gluten Free 60-Day Guarantee
⚡ While Stock Lasts — Bundle & Save

Another Month Hiding Your Smile
Or Tonight You Start Rebuilding It.

Tideglusib + hydroxyapatite. One patch. Minutes. Rebuild enamel & dentin, kill the tartar line, strengthen gums, whiten, stop the jolt. 60-day money-back. The only thing you risk is the stain.

GET PRIME® TOOTH & GUM CARE — RISK-FREE
✓ Rated 4.7★ ✓ 10,715 Reviews ✓ 60-Day Guarantee ✓ 5-in-1 Nightly Rebuild

"I put one on after brushing and forget about it. Weeks later the tartar line lifted, my gums stopped bleeding, and ice water doesn't jolt. Easiest rebuild I've ever added."

— Verified Buyer · ✓ Confirmed purchase

Prime® Tooth & Gum Care Fast-Dissolving Microneedle Patch is intended for cosmetic oral-care use. This product is not intended to diagnose, treat, cure, or prevent any disease, including cavities or periodontal disease. If you have active dental pain, infection, or a diagnosed condition, consult a licensed dentist. Discontinue use if irritation occurs. Keep out of reach of children.